The Inspector Raman has been used to monitor microwave assisted reactions, combinatorial micro reactions and common organic and inorganic reactions. Synthetic reactions are usually carried out in glass containers such as round-bottom flasks, test tubes and vacuum line containers. Since Raman is a focusing technique it is important that the focal point is optimized in the solution, and not on the glass interface. The focal point of the Inspector Raman is easily focused into the solution by a simple manual adjustment. In the example at right, we show an example of how glass can interfere while measuring acetone solvent in a round bottom flask. For this experiment, no sampling attachments were used, the Raman was collected using the standard sampling nose of the Inspector Raman. As the distance from the flask is increased, glass interference is pronounced and eventually overwhelms the spectrum. Reaction containers are easily accommodated by the Inspector Raman, and quality spectra are obtained by placing the nozzle against or near the glass surface.

In the last example, we display continuous spectra obtained by monitoring formation of an imidazole. In less than two minutes, several quality spectra are obtained in order to monitor the formation of the final product.